C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dynamin 1-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000452533 DNM1L-001 ENSG00000087470 9606 + 12:32679200-32745552 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000452533
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000452533 4.229±0.00 5.462±0.00 1.078±0.00 2.792±1.63 3.180±0.00 0.803±0.00 2.874±1.72 2.157±0.84 2.179±0.62 1.752±0.00 3.720±1.11 3.800±0.63 8.681±1.44

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000266 IMP mitochondrial fission
GO:0001836 IMP release of cytochrome c from mitochondria
GO:0003374 IDA dynamin polymerization involved in mitochondrial fission
GO:0003924 IDA:IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005777 IDA peroxisome
GO:0005794 IDA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005874 IDA microtubule
GO:0005905 IEA coated pit
GO:0006184 IDA GTP catabolic process
GO:0006897 IEA endocytosis
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008289 IEA lipid binding
GO:0010821 IMP regulation of mitochondrion organization
GO:0016020 IDA membrane
GO:0016559 IDA peroxisome fission
GO:0030054 IEA cell junction
GO:0031410 IEA cytoplasmic vesicle
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032459 IDA regulation of protein oligomerization
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043065 IMP positive regulation of apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043234 IDA protein complex
GO:0043653 IMP mitochondrial fragmentation involved in apoptotic process
GO:0045202 IEA synapse
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050714 IDA positive regulation of protein secretion
GO:0051289 IDA protein homotetramerization
GO:0061025 IDA membrane fusion
GO:0070266 IMP necroptotic process
GO:0070584 IMP mitochondrion morphogenesis
GO:0090141 TAS positive regulation of mitochondrial fission
GO:0090149 IDA membrane fission involved in mitochondrial fission
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:1900063 IMP regulation of peroxisome organization
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115749 Dnm1l-203 protein_coding Mus_musculus 0 3123
ENSMUST00000122018 Gm13719-001 processed_pseudogene Mus_musculus 0 2407
ENSMUST00000023477 Dnm1l-201 protein_coding Mus_musculus 0 2320
ENSMUST00000096229 Dnm1l-202 protein_coding Mus_musculus 0 1901
ENSMUST00000032820 Zscan26-201 protein_coding Mus_musculus 0.00000000006 75

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