C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: euchromatic histone-lysine N-methyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000460843 EHMT1-001 ENSG00000181090 9606 + 9:137619002-137836124 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000460843
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000460843 5.274±0.00 5.412±0.00 1.662±0.00 5.126±3.71 4.508±1.50 2.524±2.09 4.532±2.18 3.171±1.57 4.187±2.22 7.383±0.00 7.520±3.72 9.033±1.39 17.883±4.83

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IPI p53 binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IEA chromosome
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006306 ISS DNA methylation
GO:0008168 IDA methyltransferase activity
GO:0008270 IEA zinc ion binding
GO:0009790 ISS embryo development
GO:0016279 IDA protein-lysine N-methyltransferase activity
GO:0016568 IDA chromatin modification
GO:0016571 IDA histone methylation
GO:0018024 IDA:IEA histone-lysine N-methyltransferase activity
GO:0018026 ISS peptidyl-lysine monomethylation
GO:0018027 IDA peptidyl-lysine dimethylation
GO:0034968 IEA histone lysine methylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046974 ISS histone methyltransferase activity (H3-K9 specific)
GO:0046976 ISS histone methyltransferase activity (H3-K27 specific)
GO:0051567 IEA histone H3-K9 methylation
GO:0070734 IEA histone H3-K27 methylation
GO:0070742 IEA C2H2 zinc finger domain binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102938 Ehmt1-001 protein_coding Mus_musculus 0 3818
ENSMUST00000091348 Ehmt1-002 protein_coding Mus_musculus 0 3663
ENSMUST00000114432 Ehmt1-203 protein_coding Mus_musculus 0 2510
ENSMUST00000114418 Ehmt1-202 protein_coding Mus_musculus 0 2139
ENSMUST00000046227 Ehmt1-201 protein_coding Mus_musculus 0 2139
ENSMUST00000147147 Ehmt1-003 protein_coding Mus_musculus 0 2139
ENSMUST00000139000 Ehmt1-005 processed_transcript Mus_musculus 0 2085
ENSMUST00000134775 Ehmt1-004 processed_transcript Mus_musculus 0 1147
ENSMUST00000152161 Ehmt1-007 protein_coding Mus_musculus 0 1003
ENSMUST00000152636 Ehmt1-010 processed_transcript Mus_musculus 0 787
ENSMUST00000150379 Ehmt1-006 protein_coding Mus_musculus 0 736
ENSMUST00000150836 Ehmt1-009 processed_transcript Mus_musculus 0 641
ENSMUST00000152325 Ehmt1-008 protein_coding Mus_musculus 0 636

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