C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box P3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000518685 FOXP3-003 ENSG00000049768 9606 - X:49251334-49258527 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002725 IDA negative regulation of T cell cytokine production
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 NAS cytoplasm
GO:0006338 NAS chromatin remodeling
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0008285 IDA negative regulation of cell proliferation
GO:0009615 IEP response to virus
GO:0031064 IGI negative regulation of histone deacetylation
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032693 IDA negative regulation of interleukin-10 production
GO:0032703 IDA negative regulation of interleukin-2 production
GO:0032713 IDA negative regulation of interleukin-4 production
GO:0032792 IDA negative regulation of CREB transcription factor activity
GO:0035035 IPI histone acetyltransferase binding
GO:0035066 IMP positive regulation of histone acetylation
GO:0042036 IDA negative regulation of cytokine biosynthetic process
GO:0042110 IDA T cell activation
GO:0042130 IDA negative regulation of T cell proliferation
GO:0042803 IPI protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0043029 NAS T cell homeostasis
GO:0043234 NAS protein complex
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045085 IMP negative regulation of interleukin-2 biosynthetic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046007 NAS negative regulation of activated T cell proliferation
GO:0046872 IEA metal ion binding
GO:0050710 IDA negative regulation of cytokine secretion
GO:0050777 IDA negative regulation of immune response
GO:0051059 NAS NF-kappaB binding
GO:0051525 IPI NFAT protein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045566 Foxp3-201 protein_coding Mus_musculus 0 1007
ENSMUST00000115738 Foxp3-003 protein_coding Mus_musculus 0 1007
ENSMUST00000115739 Foxp3-002 protein_coding Mus_musculus 0 1007
ENSMUST00000115740 Foxp3-001 protein_coding Mus_musculus 0 1007
ENSDART00000122918 foxp4-202 protein_coding Danio_rerio 2e-30 137
ENSDART00000114288 foxp4-201 protein_coding Danio_rerio 2e-30 137

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