C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: CASP2 and RIPK1 domain containing adaptor with death domain
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000542893 CRADD-002 ENSG00000169372 9606 + 12:93677717-93850756 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006977 IMP DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165 IEA signal transduction
GO:0008625 IC extrinsic apoptotic signaling pathway via death domain receptors
GO:0030674 IPI protein binding, bridging
GO:0042981 IEA regulation of apoptotic process
GO:0070513 IPI death domain binding
GO:0071260 IEP cellular response to mechanical stimulus
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

No Homologs available.

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