C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: TP53 regulated inhibitor of apoptosis 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000546954 TRIAP1-001 ENSG00000170855 9606 - 12:120443961-120446412 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000546954
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000546954 7.455±0.00 13.311±0.00 1.343±0.00 6.451±2.20 9.571±6.14 7.141±4.30 3.038±2.30 11.262±0.48 8.084±3.71 3.254±2.03 7.174±0.06 10.501±5.83 17.030±7.62 10.972±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CQ CIL_0009CQ_0001 VISTA 12:119991644-120595694
CIL_0007ZA CIL_0007ZA_0001 VISTA 12:120240385-120840841
CIL_0002ZM CIL_0002ZM_0001 CGP 12:120438198-120460006

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002039 IPI p53 binding
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005758 IDA mitochondrial intermembrane space
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0015914 IDA phospholipid transport
GO:0030330 IDA DNA damage response, signal transduction by p53 class mediator
GO:0034644 IDA cellular response to UV
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043234 IDA protein complex
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria
GO:0097035 IMP regulation of membrane lipid distribution
GO:1902166 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1990050 IDA phosphatidic acid transporter activity
GO:2001140 IDA positive regulation of phospholipid transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031508 Triap1-001 protein_coding Mus_musculus 0 346

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