C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAS guanyl releasing protein 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000589474 RASGRP4-001 ENSG00000171777 9606 - 19:38409058-38426305 nonsense_mediated_decay

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 IDA Ras guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007169 NAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007202 NAS activation of phospholipase C activity
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008277 NAS regulation of G-protein coupled receptor protein signaling pathway
GO:0008283 IDA cell proliferation
GO:0009991 IDA response to extracellular stimulus
GO:0016020 IDA membrane
GO:0016049 IDA cell growth
GO:0019992 TAS diacylglycerol binding
GO:0030099 TAS myeloid cell differentiation
GO:0030742 NAS GTP-dependent protein binding
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0046579 IDA positive regulation of Ras protein signal transduction
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000161522 Rasgrp4-008 protein_coding Mus_musculus 0 1975

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