C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: titin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000591111 TTN-019 ENSG00000155657 9606 - 2:178525989-178807423 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungENST00000591111
Transcript ID Lung
ENST00000591111 2.761±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YX CIL_0000YX_0001 CGP 2:178480468-178830802
CIL_0000YW CIL_0000YW_0001 CGP 2:178525989-179050086

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000794 IDA condensed nuclear chromosome
GO:0002020 IPI protease binding
GO:0002576 TAS platelet degranulation
GO:0003300 IMP cardiac muscle hypertrophy
GO:0003676 IEA nucleic acid binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005516 TAS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005865 IDA striated muscle thin filament
GO:0006468 IEA protein phosphorylation
GO:0006936 NAS muscle contraction
GO:0006941 TAS striated muscle contraction
GO:0007076 IEP mitotic chromosome condensation
GO:0007596 TAS blood coagulation
GO:0008307 IMP structural constituent of muscle
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0030018 IDA Z disc
GO:0030049 TAS muscle filament sliding
GO:0030168 TAS platelet activation
GO:0030240 IMP skeletal muscle thin filament assembly
GO:0030241 IMP skeletal muscle myosin thick filament assembly
GO:0031430 IDA M band
GO:0031433 ISS telethonin binding
GO:0031674 IDA I band
GO:0035995 TAS detection of muscle stretch
GO:0042802 IPI identical protein binding
GO:0042805 IPI actinin binding
GO:0043621 IDA protein self-association
GO:0045214 IMP sarcomere organization
GO:0045859 IMP regulation of protein kinase activity
GO:0048739 IMP cardiac muscle fiber development
GO:0048769 IMP sarcomerogenesis
GO:0050790 IMP regulation of catalytic activity
GO:0051015 IDA actin filament binding
GO:0051371 IPI muscle alpha-actinin binding
GO:0051592 IDA response to calcium ion
GO:0055003 IMP cardiac myofibril assembly
GO:0055008 IMP cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0097493 TAS structural molecule activity conferring elasticity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111882 Ttn-202 protein_coding Mus_musculus 0 84860
ENSMUST00000111846 Ttn-201 protein_coding Mus_musculus 0 84010
ENSMUST00000099981 Ttn-019 protein_coding Mus_musculus 0 82800
ENSMUST00000011934 Ttn-001 protein_coding Mus_musculus 0 82600
ENSMUST00000134720 Ttn-002 protein_coding Mus_musculus 0 20920
ENSMUST00000099980 Ttn-021 protein_coding Mus_musculus 0 9769
ENSMUST00000148747 Ttn-006 protein_coding Mus_musculus 0 9616
ENSDART00000017677 ttna-202 protein_coding Danio_rerio 0 5548
ENSDART00000126871 ttna-001 protein_coding Danio_rerio 0 5548
ENSDART00000109099 ttna-203 protein_coding Danio_rerio 0 5437
ENSMUST00000138542 Ttn-018 protein_coding Mus_musculus 0 3376
ENSMUST00000140091 Ttn-004 protein_coding Mus_musculus 0 2700
ENSMUST00000123804 Ttn-005 retained_intron Mus_musculus 0 2529
ENSMUST00000128071 Ttn-016 protein_coding Mus_musculus 0 1659
ENSMUST00000147048 Ttn-003 retained_intron Mus_musculus 0 1631
ENSDART00000002299 ttnb-202 protein_coding Danio_rerio 0 1343
ENSDART00000125953 ttnb-001 protein_coding Danio_rerio 0 1343
ENSMUST00000152185 Ttn-013 protein_coding Mus_musculus 0 1053
ENSMUST00000155365 Ttn-017 protein_coding Mus_musculus 0 941
ENSMUST00000130915 Ttn-015 protein_coding Mus_musculus 0 941
ENSMUST00000149616 Ttn-014 protein_coding Mus_musculus 0 941
ENSMUST00000123448 Ttn-023 retained_intron Mus_musculus 0 769
ENSMUST00000139832 Ttn-008 processed_transcript Mus_musculus 0 671
ENSDART00000000908 ttnb-201 protein_coding Danio_rerio 0 379
ENSDART00000141122 ttnb-002 protein_coding Danio_rerio 0 379
ENSMUST00000142251 Ttn-012 protein_coding Mus_musculus 0 196
ENSMUST00000150741 Ttn-020 protein_coding Mus_musculus 9.80909e-45 191
ENSMUST00000137854 Ttn-010 protein_coding Mus_musculus 4.00001e-40 176

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