C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000612484 HUWE1-002 ENSG00000086758 9606 - X:53532096-53654107 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastMuscleENST00000612484
Transcript ID Breast Muscle
ENST00000612484 2.471±0.00 5.096±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0003677 ISS DNA binding
GO:0004842 IDA:IEA ubiquitin-protein transferase activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0006284 IMP base-excision repair
GO:0006513 IDA protein monoubiquitination
GO:0016020 IDA membrane
GO:0016574 IDA histone ubiquitination
GO:0016874 IEA ligase activity
GO:0030154 IEA cell differentiation
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112622 Huwe1-001 protein_coding Mus_musculus 0 18970
ENSMUST00000026292 Huwe1-002 protein_coding Mus_musculus 0 18950
ENSMUST00000138023 Huwe1-016 nonsense_mediated_decay Mus_musculus 0 4711
ENSMUST00000153687 Huwe1-003 nonsense_mediated_decay Mus_musculus 0 3690
ENSMUST00000150020 Huwe1-005 retained_intron Mus_musculus 0 2230
ENSMUST00000130243 Huwe1-004 retained_intron Mus_musculus 0 2230
ENSMUST00000131786 Huwe1-006 retained_intron Mus_musculus 0 2230
ENSMUST00000137816 Huwe1-015 retained_intron Mus_musculus 0 992
ENSMUST00000130234 Huwe1-023 retained_intron Mus_musculus 0 854
ENSMUST00000147666 Huwe1-008 processed_transcript Mus_musculus 0 771
ENSMUST00000123306 Huwe1-019 nonsense_mediated_decay Mus_musculus 0 665
ENSMUST00000150426 Huwe1-018 retained_intron Mus_musculus 0 616
ENSMUST00000139909 Huwe1-021 retained_intron Mus_musculus 0 505
ENSMUST00000132453 Huwe1-020 retained_intron Mus_musculus 0 379
ENSMUST00000133051 Huwe1-022 retained_intron Mus_musculus 0 348
ENSMUST00000138566 Huwe1-014 nonsense_mediated_decay Mus_musculus 1e-17 99
ENSDART00000156280 si:ch211-195b15.7-001 protein_coding Danio_rerio 0.000001 60
ENSDART00000154950 si:ch211-195b15.7-002 retained_intron Danio_rerio 0.0000003 60
ENSDART00000022660 si:ch211-195b15.7-201 protein_coding Danio_rerio 0.000001 60

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