C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thyroid hormone receptor alpha a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000000151 thraa 7955 - 3:34773318-34838901 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000000160 thraa-001 34782574-34838901 protein_coding
  ENSDART00000151127 thraa-002 34773318-34803178 protein_coding
  ENSDART00000151575 thraa-003 34786510-34792033 retained_intron
  ENSDART00000151633 thraa-004 34828875-34838837 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000000160ENSDART00000151127
Transcript ID Brain Heart Kidney Muscle
ENSDART00000000160 2.615±0.75 1.286±0.56 1.933±1.53 0.920±0.00
ENSDART00000151127 N/A 0.894±0.00 N/A 2.498±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001076 IDA RNA polymerase II transcription factor binding transcription factor activity
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004887 IEA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007275 IEA multicellular organismal development
GO:0008270 IEA zinc ion binding
GO:0009725 IDA response to hormone
GO:0030522 IDA intracellular receptor signaling pathway
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-dependent
GO:0045893 IDA positive regulation of transcription, DNA-dependent
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000126351 THRA thyroid hormone receptor, alpha protein_coding Homo_sapiens
ENSMUSG00000058756 Thra thyroid hormone receptor alpha protein_coding Mus_musculus

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