C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: scribbled homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000000861 scrib 7955 + 7:43889852-44003019 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000021013 scrib-001 43946691-43987705 protein_coding
  ENSDART00000074212 scrib-201 43889852-44003019 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000074212
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000074212 3.286±1.31 2.893±2.67 1.913±0.71 0.231±0.00 1.332±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000132 IMP establishment of mitotic spindle orientation
GO:0001764 IMP neuron migration
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 ISS plasma membrane
GO:0005913 ISS cell-cell adherens junction
GO:0007275 IEA multicellular organismal development
GO:0008283 ISS cell proliferation
GO:0014021 IMP secondary neural tube formation
GO:0016020 IDA membrane
GO:0016337 ISS cell-cell adhesion
GO:0016477 ISS cell migration
GO:0030054 IEA cell junction
GO:0030154 IEA cell differentiation
GO:0031252 ISS cell leading edge
GO:0032863 ISS activation of Rac GTPase activity
GO:0035089 ISS establishment of apical/basal cell polarity
GO:0042734 ISS presynaptic membrane
GO:0043065 ISS positive regulation of apoptotic process
GO:0045211 ISS postsynaptic membrane
GO:0045930 ISS negative regulation of mitotic cell cycle
GO:0050918 ISS positive chemotaxis
GO:0060027 IGI convergent extension involved in gastrulation
GO:0060561 ISS apoptotic process involved in morphogenesis
GO:0097475 IGI motor neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000180900 SCRIB scribbled planar cell polarity protein protein_coding Homo_sapiens
ENSMUSG00000022568 Scrib scribbled homolog (Drosophila) protein_coding Mus_musculus

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