C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: scribbled planar cell polarity protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180900 SCRIB 9606 - 8:143790920-143815379 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320476 SCRIB-001 143790920-143815379 protein_coding
  ENST00000356994 SCRIB-002 143790920-143815379 protein_coding
  ENST00000377533 SCRIB-003 143790926-143814968 protein_coding
  ENST00000525051 SCRIB-005 143790925-143793588 retained_intron
  ENST00000526832 SCRIB-004 143790925-143804151 protein_coding
  ENST00000531163 SCRIB-008 143790925-143791542 retained_intron
  ENST00000531942 SCRIB-007 143805252-143808677 protein_coding
  ENST00000546337 SCRIB-009 143792609-143794236 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320476ENST00000356994ENST00000526832ENST00000531163
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320476 8.615±0.00 4.955±0.00 2.244±1.67 2.910±0.00 4.605±3.05 2.619±0.00 6.907±0.00 2.075±0.30 N/A N/A 16.527±8.62 6.425±1.68 8.202±0.07
ENST00000356994 N/A N/A 2.432±1.76 2.057±0.00 N/A 1.147±0.00 2.067±0.00 0.954±0.00 N/A 9.403±7.32 N/A 2.204±0.00 2.075±0.00
ENST00000526832 N/A 4.030±0.00 N/A 6.386±0.00 6.635±0.00 N/A 5.418±0.00 3.847±0.00 3.894±0.00 N/A 18.183±0.00 5.644±0.43 7.129±0.01
ENST00000531163 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.329±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008C2 CIL_0008C2_0001 VISTA 8:143231340-143832399
CIL_0002GT CIL_0002GT_0001 CGP 8:143790920-143829859

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0001921 IMP positive regulation of receptor recycling
GO:0002093 IEA auditory receptor cell morphogenesis
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005913 IDA cell-cell adherens junction
GO:0008105 IEA asymmetric protein localization
GO:0008283 IDA cell proliferation
GO:0016032 IEA viral process
GO:0016080 IEA synaptic vesicle targeting
GO:0016323 IEA basolateral plasma membrane
GO:0016331 IEA morphogenesis of embryonic epithelium
GO:0016337 IGI single organismal cell-cell adhesion
GO:0016477 IMP cell migration
GO:0021747 IEA cochlear nucleus development
GO:0031252 IDA cell leading edge
GO:0032863 IMP activation of Rac GTPase activity
GO:0034750 IDA Scrib-APC-beta-catenin complex
GO:0035089 IMP establishment of apical/basal cell polarity
GO:0035748 IEA myelin sheath abaxonal region
GO:0042060 IEA wound healing
GO:0042734 IDA presynaptic membrane
GO:0042995 IEA cell projection
GO:0043065 IMP positive regulation of apoptotic process
GO:0043615 IEA astrocyte cell migration
GO:0045211 IDA postsynaptic membrane
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0048488 IEA synaptic vesicle endocytosis
GO:0050918 IMP positive chemotaxis
GO:0060088 IEA auditory receptor cell stereocilium organization
GO:0060561 IMP apoptotic process involved in morphogenesis
GO:0060603 ISS mammary gland duct morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071896 IMP protein localization to adherens junction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000861 scrib scribbled homolog (Drosophila) protein_coding Danio_rerio
ENSMUSG00000022568 Scrib scribbled homolog (Drosophila) protein_coding Mus_musculus

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