C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelium-specific receptor tyrosine kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000004105 tie1 7955 - 6:33681319-33706524 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000003701 tie1-001 33681319-33706524 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000003701
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000003701 2.626±0.73 12.258±1.13 4.523±0.00 0.526±0.00 2.676±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003N3 CIL_0003N3_0001 CGP 6:33646925-33706524

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004866 IEA endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007507 IGI heart development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0071603 IMP endothelial cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000066056 TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 protein_coding Homo_sapiens
ENSMUSG00000033191 Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 protein_coding Mus_musculus

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