C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Bruton agammaglobulinemia tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000004433 btk 7955 - 14:40388026-40426337 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000009758 btk-201 40388852-40409505 protein_coding
  ENSDART00000148737 btk-001 40388026-40426337 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000009758ENSDART00000148737
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000009758 0.234±0.00 1.232±0.42 N/A N/A 0.471±0.00
ENSDART00000148737 0.501±0.18 2.086±0.74 5.974±4.53 0.317±0.00 1.070±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0009952 IGI anterior/posterior pattern specification
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030178 IGI negative regulation of Wnt receptor signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0060828 IGI regulation of canonical Wnt receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000010671 BTK Bruton agammaglobulinemia tyrosine kinase protein_coding Homo_sapiens
ENSMUSG00000031264 Btk Bruton agammaglobulinemia tyrosine kinase protein_coding Mus_musculus

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