C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: rho-associated, coiled-coil containing protein kinase 2b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000004877 rock2b 7955 - 20:33674217-33729379 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000002777 rock2b-201 33674217-33729379 protein_coding
  ENSDART00000147168 rock2b-002 33693954-33700284 protein_coding
  ENSDART00000152839 rock2b-005 33680771-33710988 processed_transcript
  ENSDART00000153420 rock2b-004 33681942-33713207 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000002777ENSDART00000147168ENSDART00000152839
Transcript ID Brain Heart Kidney Liver
ENSDART00000002777 0.110±0.07 1.327±0.75 1.923±0.00 0.375±0.00
ENSDART00000147168 0.373±0.21 1.483±0.71 N/A N/A
ENSDART00000152839 0.499±0.06 0.427±0.00 N/A 2.130±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017048 IEA Rho GTPase binding
GO:0035556 IEA intracellular signal transduction
GO:0046872 IEA metal ion binding
GO:0060287 IMP epithelial cilium movement involved in determination of left/right asymmetry
GO:0070121 IMP Kupffer's vesicle development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000134318 ROCK2 Rho-associated, coiled-coil containing protein kinase 2 protein_coding Homo_sapiens
ENSMUSG00000020580 Rock2 Rho-associated coiled-coil containing protein kinase 2 protein_coding Mus_musculus

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