C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho-associated coiled-coil containing protein kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020580 Rock2 10090 + 12:16894978-16988274 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020904 Rock2-201 16894978-16988274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020904
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020904 6.600±0.99 3.709±0.66 18.660±3.41 19.503±16.72 5.541±0.81 5.698±1.11 5.869±2.13 3.232±1.10 2.041±1.40 6.769±3.02 6.549±2.86 8.095±7.60 19.806±11.45 1.988±1.46

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IGI neural tube closure
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005813 IDA centrosome
GO:0006468 IEA protein phosphorylation
GO:0007266 ISO Rho protein signal transduction
GO:0008625 IGI extrinsic apoptotic signaling pathway via death domain receptors
GO:0010825 IMP positive regulation of centrosome duplication
GO:0016525 IEA negative regulation of angiogenesis
GO:0017048 IEA Rho GTPase binding
GO:0030036 IGI actin cytoskeleton organization
GO:0031616 IDA spindle pole centrosome
GO:0036464 IEA cytoplasmic ribonucleoprotein granule
GO:0044822 IEA poly(A) RNA binding
GO:0045616 IEA regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0048813 IGI dendrite morphogenesis
GO:0051298 IEA centrosome duplication

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004877 rock2b rho-associated, coiled-coil containing protein kinase 2b protein_coding Danio_rerio
ENSDARG00000017500 rock2a rho-associated, coiled-coil containing protein kinase 2a protein_coding Danio_rerio
ENSDARG00000086649 ROCK2 (3 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSDARG00000087746 ROCK2 (4 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSDARG00000088086 ROCK2 (5 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSDARG00000088333 ROCK2 (6 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSDARG00000088620 ROCK2 (7 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSDARG00000089492 ROCK2 (8 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSDARG00000090999 ROCK2 (9 of 9) Rho-associated, coiled-coil containing protein kinase 2 protein_coding Danio_rerio
ENSG00000134318 ROCK2 Rho-associated, coiled-coil containing protein kinase 2 protein_coding Homo_sapiens

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