C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spleen tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000008186 syk 7955 - 10:5539534-5584889 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000005292 syk-201 5540466-5571739 protein_coding
  ENSDART00000141943 syk-001 5539534-5584889 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000005292ENSDART00000141943
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000005292 2.086±0.00 1.001±0.25 N/A 0.239±0.00 1.125±0.00
ENSDART00000141943 4.077±1.39 3.210±2.60 14.075±8.76 N/A 0.907±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001946 IGI lymphangiogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IEA intracellular signal transduction
GO:0090050 IMP positive regulation of cell migration involved in sprouting angiogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000165025 SYK spleen tyrosine kinase protein_coding Homo_sapiens
ENSMUSG00000021457 Syk spleen tyrosine kinase protein_coding Mus_musculus

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