C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000008986 e2f7 7955 - 4:2401851-2416355 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000007196 e2f7-201 2403045-2415503 protein_coding
  ENSDART00000140760 e2f7-001 2401851-2416355 protein_coding
  ENSDART00000150619 e2f7-002 2412507-2416320 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000007196ENSDART00000140760ENSDART00000150619
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000007196 0.132±0.00 0.135±0.00 N/A N/A N/A
ENSDART00000140760 0.259±0.16 0.211±0.09 0.263±0.02 0.014±0.00 0.061±0.00
ENSDART00000150619 0.323±0.19 N/A 0.348±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BB CIL_0002BB_0001 CGP 4:2382639-2416355

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001047 ISS core promoter binding
GO:0001890 ISS placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005622 ISS intracellular
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007049 IEA cell cycle
GO:0008285 ISS negative regulation of cell proliferation
GO:0030330 ISS DNA damage response, signal transduction by p53 class mediator
GO:0032466 ISS negative regulation of cytokinesis
GO:0032877 ISS positive regulation of DNA endoreduplication
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060707 ISS trophoblast giant cell differentiation
GO:0060718 ISS chorionic trophoblast cell differentiation
GO:0070365 ISS hepatocyte differentiation
GO:0071930 ISS negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:2000134 ISS negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000165891 E2F7 E2F transcription factor 7 protein_coding Homo_sapiens
ENSMUSG00000020185 E2f7 E2F transcription factor 7 protein_coding Mus_musculus

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