C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165891 E2F7 9606 - 12:77021247-77065580 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322886 E2F7-001 77021247-77065580 protein_coding
  ENST00000416496 E2F7-004 77021248-77065563 protein_coding
  ENST00000547316 E2F7-005 77055878-77065550 protein_coding
  ENST00000550669 E2F7-003 77027944-77065567 protein_coding
  ENST00000551058 E2F7-007 77044534-77050746 protein_coding
  ENST00000551558 E2F7-002 77045622-77065563 retained_intron
  ENST00000552907 E2F7-006 77034006-77050741 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322886ENST00000416496ENST00000547316ENST00000550669ENST00000551058ENST00000551558ENST00000552907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322886 0.019±0.00 N/A N/A 0.050±0.00 N/A N/A N/A N/A N/A 0.011±0.00 N/A 0.306±0.13 0.152±0.05 0.815±0.19
ENST00000416496 N/A 0.041±0.00 0.038±0.00 N/A 0.037±0.00 0.057±0.00 N/A 0.032±0.00 0.005±0.00 0.084±0.00 0.003±0.00 0.044±0.01 0.187±0.00 N/A
ENST00000547316 N/A N/A N/A 0.134±0.00 N/A N/A N/A N/A N/A N/A 0.080±0.00 N/A N/A N/A
ENST00000550669 N/A N/A N/A N/A 0.396±0.00 N/A N/A N/A N/A N/A 0.043±0.00 0.422±0.00 N/A 1.296±0.00
ENST00000551058 N/A N/A N/A N/A 0.145±0.00 1.104±0.00 0.068±0.00 N/A N/A 0.588±0.00 N/A N/A 0.461±0.00 N/A
ENST00000551558 0.025±0.00 N/A N/A 0.020±0.00 N/A N/A N/A N/A 0.136±0.00 N/A N/A N/A N/A N/A
ENST00000552907 N/A N/A N/A 0.206±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BB CIL_0002BB_0002 CGP 12:76858715-77065580

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001890 ISS placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008285 IMP negative regulation of cell proliferation
GO:0030330 IDA DNA damage response, signal transduction by p53 class mediator
GO:0032466 ISS negative regulation of cytokinesis
GO:0032877 ISS positive regulation of DNA endoreduplication
GO:0042802 IPI identical protein binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060707 ISS trophoblast giant cell differentiation
GO:0060718 ISS chorionic trophoblast cell differentiation
GO:0070365 ISS hepatocyte differentiation
GO:0071930 IDA negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:2000134 ISS negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008986 e2f7 E2F transcription factor 7 protein_coding Danio_rerio
ENSMUSG00000020185 E2f7 E2F transcription factor 7 protein_coding Mus_musculus

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