C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020185 E2f7 10090 + 10:110745439-110787384 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073781 E2f7-001 110745468-110787384 protein_coding
  ENSMUST00000172574 E2f7-007 110754262-110756247 processed_transcript
  ENSMUST00000173294 E2f7-006 110745439-110748146 processed_transcript
  ENSMUST00000173471 E2f7-002 110745513-110785510 protein_coding
  ENSMUST00000173634 E2f7-005 110745572-110754577 protein_coding
  ENSMUST00000173948 E2f7-008 110754332-110774652 nonsense_mediated_decay
  ENSMUST00000174593 E2f7-009 110763856-110765754 retained_intron
  ENSMUST00000174810 E2f7-004 110745468-110768139 retained_intron
  ENSMUST00000174857 E2f7-003 110745465-110756637 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073781ENSMUST00000172574ENSMUST00000173294ENSMUST00000173471ENSMUST00000173948ENSMUST00000174593ENSMUST00000174810ENSMUST00000174857
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073781 0.038±0.00 0.196±0.13 0.054±0.00 0.699±0.71 0.149±0.03 0.268±0.06 0.041±0.01 0.034±0.01 0.597±0.74 0.140±0.07 0.040±0.02 0.656±0.52 5.168±5.06 0.392±0.00
ENSMUST00000172574 N/A N/A N/A N/A N/A N/A 0.093±0.00 N/A 0.122±0.00 N/A N/A 0.622±0.00 N/A N/A
ENSMUST00000173294 N/A 0.665±0.11 N/A N/A N/A 0.556±0.03 N/A 0.159±0.00 N/A N/A 0.187±0.00 0.539±0.03 N/A N/A
ENSMUST00000173471 N/A 0.098±0.04 N/A N/A 0.258±0.00 0.093±0.01 0.083±0.04 0.034±0.01 0.056±0.00 N/A 0.016±0.01 0.262±0.10 3.153±2.14 N/A
ENSMUST00000173948 N/A N/A N/A N/A N/A N/A 0.140±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000174593 N/A N/A N/A 0.084±0.00 N/A N/A N/A N/A 0.091±0.00 N/A 0.266±0.00 N/A N/A N/A
ENSMUST00000174810 N/A N/A N/A N/A N/A N/A N/A 0.030±0.01 N/A N/A N/A N/A N/A N/A
ENSMUST00000174857 N/A 0.045±0.01 N/A 0.006±0.00 0.052±0.01 N/A 0.025±0.00 0.012±0.00 N/A N/A 0.017±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001890 IMP placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0008285 IDA negative regulation of cell proliferation
GO:0030330 ISS DNA damage response, signal transduction by p53 class mediator
GO:0032466 IMP negative regulation of cytokinesis
GO:0032877 IMP positive regulation of DNA endoreduplication
GO:0042802 IEA identical protein binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0060707 IMP trophoblast giant cell differentiation
GO:0060718 IMP chorionic trophoblast cell differentiation
GO:0070365 IMP hepatocyte differentiation
GO:0071930 ISS negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008986 e2f7 E2F transcription factor 7 protein_coding Danio_rerio
ENSG00000165891 E2F7 E2F transcription factor 7 protein_coding Homo_sapiens

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