C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA fragmentation factor, beta polypeptide (caspase-activated DNase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000009748 dffb 7955 + 8:22884783-22890697 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000005989 dffb-001 22884783-22890697 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000005989
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000005989 1.682±0.67 2.756±0.97 7.846±3.14 0.328±0.00 0.910±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IBA nuclear chromatin
GO:0004536 IBA deoxyribonuclease activity
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006309 IEA apoptotic DNA fragmentation
GO:0006915 IEA apoptotic process
GO:0016787 IEA hydrolase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000169598 DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) protein_coding Homo_sapiens
ENSMUSG00000029027 Dffb DNA fragmentation factor, beta subunit protein_coding Mus_musculus

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