C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA fragmentation factor, beta subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029027 Dffb 10090 - 4:153964449-153975126 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030893 Dffb-001 153964449-153975126 protein_coding
  ENSMUST00000133607 Dffb-003 153969130-153975051 processed_transcript
  ENSMUST00000142671 Dffb-002 153972487-153975057 retained_intron
  ENSMUST00000154458 Dffb-004 153974503-153975081 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030893ENSMUST00000133607ENSMUST00000142671ENSMUST00000154458
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030893 2.405±0.89 1.428±0.57 2.635±0.35 4.927±0.83 4.158±0.81 3.870±0.35 1.535±0.73 1.944±0.55 3.798±2.56 3.173±0.36 0.771±0.04 2.850±1.39 1.612±0.74 1.173±0.78
ENSMUST00000133607 N/A 2.545±0.45 N/A N/A 2.059±0.00 1.605±0.09 N/A N/A N/A N/A N/A 2.700±1.23 N/A 0.872±0.15
ENSMUST00000142671 2.344±0.00 2.635±1.15 N/A 9.617±0.00 2.627±0.00 2.104±0.00 N/A 0.948±0.11 0.990±0.38 N/A 0.947±0.06 3.222±1.38 2.422±0.82 1.625±0.28
ENSMUST00000154458 3.711±0.00 2.332±0.52 N/A N/A 3.864±0.00 3.890±0.59 N/A 2.212±0.00 1.086±0.02 4.288±0.00 N/A 6.324±2.14 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IBA nuclear chromatin
GO:0003677 IDA DNA binding
GO:0004518 IDA nuclease activity
GO:0004536 IBA deoxyribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 ISO nucleus
GO:0006309 IBA apoptotic DNA fragmentation
GO:0007420 IEA brain development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009748 dffb DNA fragmentation factor, beta polypeptide (caspase-activated DNase) protein_coding Danio_rerio
ENSG00000169598 DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) protein_coding Homo_sapiens

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