C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000010085 p4ha2 7955 - 21:41503345-41537355 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000024137 p4ha2-201 41503351-41537355 protein_coding
  ENSDART00000122352 p4ha2-001 41503345-41522812 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000024137ENSDART00000122352
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000024137 2.891±0.37 8.437±0.00 0.649±0.00 0.678±0.00 7.990±0.00
ENSDART00000122352 N/A 6.056±0.00 N/A 0.394±0.00 3.349±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004656 IEA procollagen-proline 4-dioxygenase activity
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0016491 IEA oxidoreductase activity
GO:0016702 IEA oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418 IEA L-ascorbic acid binding
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000072682 P4HA2 prolyl 4-hydroxylase, alpha polypeptide II protein_coding Homo_sapiens
ENSMUSG00000018906 P4ha2 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide protein_coding Mus_musculus

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