C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: flap structure-specific endonuclease 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000011404 fen1 7955 + 24:11681062-11691834 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000024224 fen1-201 11681062-11691834 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000024224
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000024224 2.956±2.00 2.710±1.71 6.861±6.32 0.798±0.00 2.072±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003824 IEA catalytic activity
GO:0004518 IEA nuclease activity
GO:0004519 IEA endonuclease activity
GO:0004527 IEA exonuclease activity
GO:0005634 IEA nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0005739 IEA mitochondrion
GO:0006260 IEA DNA replication
GO:0006281 IEA DNA repair
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0016787 IEA hydrolase activity
GO:0016788 IEA hydrolase activity, acting on ester bonds
GO:0046872 IEA metal ion binding
GO:0060041 IMP retina development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000168496 FEN1 flap structure-specific endonuclease 1 protein_coding Homo_sapiens
ENSMUSG00000024742 Fen1 flap structure specific endonuclease 1 protein_coding Mus_musculus

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