C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: flap structure specific endonuclease 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024742 Fen1 10090 - 19:10199132-10204169 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025651 Fen1-004 10199138-10204068 protein_coding
  ENSMUST00000116542 Fen1-002 10199138-10203943 protein_coding
  ENSMUST00000142241 Fen1-003 10199142-10203894 protein_coding
  ENSMUST00000156291 Fen1-001 10199132-10204169 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENSMUST00000025651ENSMUST00000116542ENSMUST00000142241ENSMUST00000156291
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025651 4.045±1.64 4.908±0.97 2.052±0.24 4.328±0.00 3.736±0.04 3.294±0.90 22.941±14.61 2.970±0.04 1.702±0.10 6.108±2.20 10.515±5.25 7.393±0.00
ENSMUST00000116542 N/A N/A 2.230±0.63 5.936±1.26 3.668±0.00 2.869±0.54 29.943±13.54 2.363±0.02 1.534±0.10 8.277±1.84 13.098±5.45 N/A
ENSMUST00000142241 2.546±0.00 3.549±0.00 N/A 2.491±0.00 N/A 3.402±0.77 N/A 1.941±0.12 1.756±0.19 6.581±0.00 20.115±0.00 N/A
ENSMUST00000156291 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.235±0.26 N/A 8.668±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WT CIL_0007WT_0002 VISTA 19:10121785-10724671

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003677 IDA DNA binding
GO:0004523 IEA RNA-DNA hybrid ribonuclease activity
GO:0004527 IDA exonuclease activity
GO:0005515 IEA protein binding
GO:0005634 TAS nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0005739 IEA mitochondrion
GO:0006260 IMP DNA replication
GO:0006281 IMP DNA repair
GO:0006284 IEA base-excision repair
GO:0007613 IEA memory
GO:0008409 IEA 5'-3' exonuclease activity
GO:0016020 IEA membrane
GO:0017108 IEA 5'-flap endonuclease activity
GO:0030145 IDA manganese ion binding
GO:0043137 IEA DNA replication, removal of RNA primer
GO:0048256 IDA flap endonuclease activity
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011404 fen1 flap structure-specific endonuclease 1 protein_coding Danio_rerio
ENSG00000168496 FEN1 flap structure-specific endonuclease 1 protein_coding Homo_sapiens

Loading