C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1Bb
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000011496 ppm1bb 7955 + 12:26960278-27012961 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000011662 ppm1bb-001 26960279-27012961 protein_coding
  ENSDART00000153253 ppm1bb-003 26995964-27005558 processed_transcript
  ENSDART00000153333 ppm1bb-002 26960278-27000858 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000011662
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000011662 33.753±4.50 12.344±9.37 3.739±3.62 2.246±0.00 12.217±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0003824 IEA catalytic activity
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0006470 IEA protein dephosphorylation
GO:0016787 IEA hydrolase activity
GO:0030145 IEA manganese ion binding
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000138032 PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B protein_coding Homo_sapiens
ENSMUSG00000061130 Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform protein_coding Mus_musculus

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