C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1B, magnesium dependent, beta isoform
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000061130 Ppm1b 10090 + 17:84956741-85023991 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000080217 Ppm1b-201 84958001-85014776 protein_coding
  ENSMUST00000112304 Ppm1b-202 84958001-85017128 protein_coding
  ENSMUST00000112305 Ppm1b-203 84956741-85023991 protein_coding
  ENSMUST00000112307 Ppm1b-204 84993673-85023991 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080217ENSMUST00000112304ENSMUST00000112305ENSMUST00000112307
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080217 4.174±0.52 4.711±0.00 8.860±0.82 13.867±6.03 2.607±0.49 3.464±0.84 7.339±1.15 3.416±0.69 9.295±3.73 5.023±1.67 16.819±1.40 5.805±1.95 6.892±2.20 N/A
ENSMUST00000112304 6.654±0.47 6.195±1.43 15.751±0.46 11.194±0.94 5.739±1.42 5.356±1.65 10.299±1.03 11.179±1.79 14.937±1.90 9.131±2.23 29.707±1.96 4.838±4.07 7.962±3.44 N/A
ENSMUST00000112305 N/A N/A N/A N/A 6.290±0.00 N/A N/A N/A N/A N/A N/A N/A 5.481±0.82 25.231±0.00
ENSMUST00000112307 N/A N/A N/A 15.512±0.00 8.228±0.00 N/A N/A N/A N/A N/A N/A 17.899±0.00 14.957±0.00 54.956±51.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XM CIL_0001XM_0002 CGP 17:84705247-85023991
CIL_0004BC CIL_0004BC_0002 CGP 17:84956741-85064243

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005515 IEA protein binding
GO:0005829 IDA cytosol
GO:0006470 IMP protein dephosphorylation
GO:0006499 IDA N-terminal protein myristoylation
GO:0016020 IDA membrane
GO:0030145 IEA manganese ion binding
GO:0032688 IEA negative regulation of interferon-beta production
GO:0035970 IEA peptidyl-threonine dephosphorylation
GO:0042347 IEA negative regulation of NF-kappaB import into nucleus
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050687 IEA negative regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011496 ppm1bb protein phosphatase, Mg2+/Mn2+ dependent, 1Bb protein_coding Danio_rerio
ENSG00000138032 PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B protein_coding Homo_sapiens

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