C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bone morphogenetic protein receptor, type II a (serine/threonine kinase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000011941 bmpr2a 7955 - 6:12709568-12780321 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000056764 bmpr2a-001 12709568-12763808 protein_coding
  ENSDART00000148145 bmpr2a-002 12736378-12736938 retained_intron
  ENSDART00000150955 bmpr2a-003 12737002-12780321 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartLiverMuscleENSDART00000056764ENSDART00000148145
Transcript ID Heart Liver Muscle
ENSDART00000056764 1.200±0.17 0.169±0.00 0.960±0.00
ENSDART00000148145 N/A 0.575±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000JN CIL_0000JN_0001 CGP 6:12709568-12781813

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001944 IGI vasculature development
GO:0001947 IMP heart looping
GO:0003146 IMP heart jogging
GO:0004672 IEA protein kinase activity
GO:0004675 IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007178 IDA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007368 IMP determination of left/right symmetry
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030509 IMP BMP signaling pathway
GO:0048570 IMP notochord morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) protein_coding Homo_sapiens
ENSMUSG00000067336 Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) protein_coding Mus_musculus

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