C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor AP-2 beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000012667 tfap2b 7955 - 20:48367977-48386887 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000013003 tfap2b-201 48367978-48384457 protein_coding
  ENSDART00000024898 tfap2b-202 48367978-48386117 protein_coding
  ENSDART00000060539 tfap2b-203 48367978-48386071 protein_coding
  ENSDART00000132105 tfap2b-001 48367977-48386887 protein_coding
  ENSDART00000135380 tfap2b-002 48380540-48386108 protein_coding
  ENSDART00000138860 tfap2b-003 48382217-48384457 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000013003ENSDART00000024898ENSDART00000060539ENSDART00000132105
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000013003 4.549±1.04 N/A 0.535±0.00 N/A 0.606±0.00
ENSDART00000024898 8.048±2.46 N/A 0.949±0.01 N/A N/A
ENSDART00000060539 7.219±1.01 0.040±0.00 N/A 0.033±0.00 N/A
ENSDART00000132105 1.901±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MC CIL_0007MC_0007 UCNEbase 20:48330176-48617223

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000983 ISS RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0001105 ISS RNA polymerase II transcription coactivator activity
GO:0001106 ISS RNA polymerase II transcription corepressor activity
GO:0003091 ISS renal water homeostasis
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 ISS transcription coactivator activity
GO:0005634 IEA nucleus
GO:0006006 ISS glucose metabolic process
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0008284 ISS positive regulation of cell proliferation
GO:0008285 ISS negative regulation of cell proliferation
GO:0010960 ISS magnesium ion homeostasis
GO:0030510 ISS regulation of BMP signaling pathway
GO:0035136 ISS forelimb morphogenesis
GO:0035137 ISS hindlimb morphogenesis
GO:0035810 ISS positive regulation of urine volume
GO:0035909 ISS aorta morphogenesis
GO:0042593 ISS glucose homeostasis
GO:0043027 ISS cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043154 ISS negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 ISS positive regulation of neuron apoptotic process
GO:0043565 ISS sequence-specific DNA binding
GO:0045595 ISS regulation of cell differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046983 ISS protein dimerization activity
GO:0048485 ISS sympathetic nervous system development
GO:0050796 ISS regulation of insulin secretion
GO:0051216 IGI cartilage development
GO:0055062 ISS phosphate ion homeostasis
GO:0055074 ISS calcium ion homeostasis
GO:0055075 ISS potassium ion homeostasis
GO:0055078 ISS sodium ion homeostasis
GO:0072017 ISS distal tubule development
GO:0072044 ISS collecting duct development
GO:0097070 ISS ductus arteriosus closure
GO:0097275 ISS cellular ammonia homeostasis
GO:0097276 ISS cellular creatinine homeostasis
GO:0097277 ISS cellular urea homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000008196 TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) protein_coding Homo_sapiens
ENSMUSG00000025927 Tfap2b transcription factor AP-2 beta protein_coding Mus_musculus

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