C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox 1a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000014018 lhx1a 7955 - 15:27052293-27059459 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000005641 lhx1a-001 27052293-27059397 protein_coding
  ENSDART00000134373 lhx1a-002 27057623-27059459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyENSDART00000005641
Transcript ID Brain Heart Kidney
ENSDART00000005641 16.566±0.00 0.037±0.01 0.280±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ND CIL_0007ND_007O UCNEbase 15:26882303-27301709

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001657 ISS ureteric bud development
GO:0001705 ISS ectoderm formation
GO:0001706 ISS endoderm formation
GO:0001822 ISS kidney development
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0007267 ISS cell-cell signaling
GO:0007275 IEA multicellular organismal development
GO:0008045 ISS motor neuron axon guidance
GO:0008270 IEA zinc ion binding
GO:0009791 ISS post-embryonic development
GO:0009880 ISS embryonic pattern specification
GO:0009953 ISS dorsal/ventral pattern formation
GO:0010842 ISS retina layer formation
GO:0021527 ISS spinal cord association neuron differentiation
GO:0021702 ISS cerebellar Purkinje cell differentiation
GO:0021871 ISS forebrain regionalization
GO:0021937 ISS cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
GO:0040019 ISS positive regulation of embryonic development
GO:0043234 ISS protein complex
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 ISS negative regulation of transcription, DNA-dependent
GO:0045893 ISS positive regulation of transcription, DNA-dependent
GO:0046872 IEA metal ion binding
GO:0060059 ISS embryonic retina morphogenesis in camera-type eye
GO:0060322 ISS head development
GO:0060429 ISS epithelium development
GO:0061205 ISS paramesonephric duct development
GO:0072049 ISS comma-shaped body morphogenesis
GO:0072050 ISS S-shaped body morphogenesis
GO:0072077 ISS renal vesicle morphogenesis
GO:0072178 ISS nephric duct morphogenesis
GO:0090009 ISS primitive streak formation
GO:0090190 ISS positive regulation of branching involved in ureteric bud morphogenesis
GO:0097477 ISS lateral motor column neuron migration
GO:2000543 ISS positive regulation of gastrulation
GO:2000744 ISS positive regulation of anterior head development
GO:2000768 ISS positive regulation of nephron tubule epithelial cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000273706 LHX1 LIM homeobox 1 protein_coding Homo_sapiens
ENSMUSG00000018698 Lhx1 LIM homeobox protein 1 protein_coding Mus_musculus

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