C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018698 Lhx1 10090 - 11:84518284-84525535 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018842 Lhx1-001 84518284-84525535 protein_coding
  ENSMUST00000092827 Lhx1-002 84521896-84522711 protein_coding
  ENSMUST00000176503 Lhx1-003 84519706-84522067 retained_intron
  ENSMUST00000184646 Lhx1-004 84519442-84522331 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000018842ENSMUST00000092827ENSMUST00000176503ENSMUST00000184646
Transcript ID Adrenal Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000018842 0.029±0.00 8.959±6.32 N/A N/A 2.508±0.58 0.015±0.01 N/A 0.041±0.02 0.048±0.01 0.190±0.04
ENSMUST00000092827 N/A N/A N/A N/A N/A 0.117±0.02 N/A N/A N/A N/A
ENSMUST00000176503 N/A N/A N/A N/A N/A N/A 0.051±0.00 0.164±0.08 N/A N/A
ENSMUST00000184646 N/A N/A 0.093±0.00 0.022±0.00 3.981±1.22 0.013±0.01 0.025±0.00 0.095±0.07 0.068±0.00 1.893±0.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008GS CIL_0008GS_0002 VISTA 11:84076005-84677109
CIL_0008DP CIL_0008DP_0002 VISTA 11:84095730-84696774
CIL_00085M CIL_00085M_0002 VISTA 11:84181126-84782244
CIL_00085Q CIL_00085Q_0002 VISTA 11:84196288-84796920
CIL_0007ND CIL_0007ND_007N UCNEbase 11:84271978-84766400
CIL_0007YB CIL_0007YB_0004 VISTA 11:84425827-85026602
CIL_00085R CIL_00085R_0002 VISTA 11:84466073-85066769

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001655 IMP urogenital system development
GO:0001656 IEP metanephros development
GO:0001657 IMP ureteric bud development
GO:0001658 IEP branching involved in ureteric bud morphogenesis
GO:0001702 IMP gastrulation with mouth forming second
GO:0001705 IGI ectoderm formation
GO:0001706 IMP endoderm formation
GO:0001822 IMP kidney development
GO:0001823 IEP mesonephros development
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007267 IGI cell-cell signaling
GO:0007389 IGI pattern specification process
GO:0008045 IMP motor neuron axon guidance
GO:0008270 IEA zinc ion binding
GO:0009653 IMP anatomical structure morphogenesis
GO:0009791 IMP post-embryonic development
GO:0009880 IGI embryonic pattern specification
GO:0009948 IGI anterior/posterior axis specification
GO:0009952 IGI anterior/posterior pattern specification
GO:0009953 IGI dorsal/ventral pattern formation
GO:0010468 IMP regulation of gene expression
GO:0010842 IEP retina layer formation
GO:0021510 IEP spinal cord development
GO:0021517 IEP ventral spinal cord development
GO:0021527 IGI spinal cord association neuron differentiation
GO:0021537 IEP telencephalon development
GO:0021549 IGI cerebellum development
GO:0021702 IGI cerebellar Purkinje cell differentiation
GO:0021871 IGI forebrain regionalization
GO:0021937 IGI cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
GO:0032525 IMP somite rostral/caudal axis specification
GO:0035502 IEA metanephric part of ureteric bud development
GO:0035846 IMP oviduct epithelium development
GO:0035847 IMP uterine epithelium development
GO:0035849 IMP nephric duct elongation
GO:0035852 IMP horizontal cell localization
GO:0040019 IMP positive regulation of embryonic development
GO:0043234 IDA protein complex
GO:0043565 IEA sequence-specific DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0048646 IGI anatomical structure formation involved in morphogenesis
GO:0048703 IMP embryonic viscerocranium morphogenesis
GO:0048793 IEP pronephros development
GO:0060041 IEP retina development in camera-type eye
GO:0060059 IMP embryonic retina morphogenesis in camera-type eye
GO:0060065 IMP uterus development
GO:0060066 IMP oviduct development
GO:0060067 IMP cervix development
GO:0060068 IMP vagina development
GO:0060322 IGI head development
GO:0060429 IMP epithelium development
GO:0061205 IMP paramesonephric duct development
GO:0072001 IGI renal system development
GO:0072049 IMP comma-shaped body morphogenesis
GO:0072050 IMP S-shaped body morphogenesis
GO:0072077 IMP renal vesicle morphogenesis
GO:0072164 IEA mesonephric tubule development
GO:0072177 IEA mesonephric duct development
GO:0072178 IMP nephric duct morphogenesis
GO:0072224 IEA metanephric glomerulus development
GO:0072278 IEA metanephric comma-shaped body morphogenesis
GO:0072283 IEP metanephric renal vesicle morphogenesis
GO:0072284 IEP metanephric S-shaped body morphogenesis
GO:0090009 IMP primitive streak formation
GO:0090190 IMP positive regulation of branching involved in ureteric bud morphogenesis
GO:0097477 IMP lateral motor column neuron migration
GO:2000543 IMP positive regulation of gastrulation
GO:2000744 IMP positive regulation of anterior head development
GO:2000768 IMP positive regulation of nephron tubule epithelial cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007944 lhx1b LIM homeobox 1b protein_coding Danio_rerio
ENSDARG00000014018 lhx1a LIM homeobox 1a protein_coding Danio_rerio
ENSG00000273706 LHX1 LIM homeobox 1 protein_coding Homo_sapiens

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