C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000273706 LHX1 9606 + 17:36936785-36944612 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000614239 LHX1-001 36937475-36944612 protein_coding
  ENST00000616237 LHX1-003 36938460-36941394 retained_intron
  ENST00000619297 LHX1-005 36936785-36937846 processed_transcript
  ENST00000619939 LHX1-002 36937635-36941531 retained_intron
  ENST00000621767 LHX1-004 36942298-36943685 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyOvaryPlacentaTestisENST00000614239ENST00000619297ENST00000619939ENST00000621767
Transcript ID Bladder Brain Breast Colon Kidney Ovary Placenta Testis
ENST00000614239 0.843±0.00 0.022±0.00 N/A N/A 4.362±0.00 0.531±0.00 0.016±0.00 0.152±0.05
ENST00000619297 N/A N/A N/A N/A N/A N/A N/A 0.104±0.00
ENST00000619939 N/A N/A N/A 0.271±0.00 N/A N/A N/A N/A
ENST00000621767 N/A N/A 0.142±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00085R CIL_00085R_0001 VISTA 17:36355391-36956100
CIL_0007YB CIL_0007YB_0001 VISTA 17:36401446-37002205
CIL_0007YB CIL_0007YB_0003 VISTA 17:36402232-37002285
CIL_0005HV CIL_0005HV_0002 CGP 17:36601572-36944612
CIL_00085Q CIL_00085Q_0001 VISTA 17:36672050-37272645
CIL_00085M CIL_00085M_0001 VISTA 17:36678794-37279927
CIL_0008DP CIL_0008DP_0001 VISTA 17:36790335-37391543
CIL_0008GS CIL_0008GS_0001 VISTA 17:36817120-37418221
CIL_0007ND CIL_0007ND_005J UCNEbase 17:36935930-36936894
CIL_0005HW CIL_0005HW_0002 CGP 17:36936785-37056871

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001655 ISS urogenital system development
GO:0001656 IEA metanephros development
GO:0001657 ISS ureteric bud development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001702 ISS gastrulation with mouth forming second
GO:0001705 ISS ectoderm formation
GO:0001706 ISS endoderm formation
GO:0001822 ISS kidney development
GO:0001823 IEA mesonephros development
GO:0003677 IEA DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 ISS nucleus
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0007267 ISS cell-cell signaling
GO:0007389 ISS pattern specification process
GO:0007399 TAS nervous system development
GO:0008045 ISS motor neuron axon guidance
GO:0008270 IEA zinc ion binding
GO:0009653 ISS anatomical structure morphogenesis
GO:0009791 ISS post-embryonic development
GO:0009880 ISS embryonic pattern specification
GO:0009887 TAS organ morphogenesis
GO:0009948 ISS anterior/posterior axis specification
GO:0009952 ISS anterior/posterior pattern specification
GO:0009953 ISS dorsal/ventral pattern formation
GO:0010468 ISS regulation of gene expression
GO:0010842 ISS retina layer formation
GO:0021510 IEA spinal cord development
GO:0021517 IEA ventral spinal cord development
GO:0021527 ISS spinal cord association neuron differentiation
GO:0021537 IEA telencephalon development
GO:0021549 ISS cerebellum development
GO:0021702 ISS cerebellar Purkinje cell differentiation
GO:0021871 ISS forebrain regionalization
GO:0021937 ISS cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
GO:0032525 IEA somite rostral/caudal axis specification
GO:0035502 IEA metanephric part of ureteric bud development
GO:0035846 ISS oviduct epithelium development
GO:0035847 ISS uterine epithelium development
GO:0035849 IEA nephric duct elongation
GO:0035852 IEA horizontal cell localization
GO:0040019 ISS positive regulation of embryonic development
GO:0043234 ISS protein complex
GO:0043565 IEA sequence-specific DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048646 ISS anatomical structure formation involved in morphogenesis
GO:0048703 ISS embryonic viscerocranium morphogenesis
GO:0048793 IEA pronephros development
GO:0060041 IEA retina development in camera-type eye
GO:0060059 ISS embryonic retina morphogenesis in camera-type eye
GO:0060065 ISS uterus development
GO:0060066 ISS oviduct development
GO:0060067 ISS cervix development
GO:0060068 ISS vagina development
GO:0060322 ISS head development
GO:0060429 ISS epithelium development
GO:0061205 ISS paramesonephric duct development
GO:0072001 IEA renal system development
GO:0072049 ISS comma-shaped body morphogenesis
GO:0072050 ISS S-shaped body morphogenesis
GO:0072077 ISS renal vesicle morphogenesis
GO:0072164 IEA mesonephric tubule development
GO:0072177 IEA mesonephric duct development
GO:0072178 ISS nephric duct morphogenesis
GO:0072224 IEA metanephric glomerulus development
GO:0072278 IEA metanephric comma-shaped body morphogenesis
GO:0072283 IEA metanephric renal vesicle morphogenesis
GO:0072284 IEA metanephric S-shaped body morphogenesis
GO:0090009 ISS primitive streak formation
GO:0090190 ISS positive regulation of branching involved in ureteric bud morphogenesis
GO:0097477 ISS lateral motor column neuron migration
GO:2000543 ISS positive regulation of gastrulation
GO:2000744 ISS positive regulation of anterior head development
GO:2000768 ISS positive regulation of nephron tubule epithelial cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007944 lhx1b LIM homeobox 1b protein_coding Danio_rerio
ENSDARG00000014018 lhx1a LIM homeobox 1a protein_coding Danio_rerio
ENSMUSG00000018698 Lhx1 LIM homeobox protein 1 protein_coding Mus_musculus

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