C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CHK1 checkpoint homolog (S. pombe)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000014385 chek1 7955 + 21:21673131-21680230 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000065538 chek1-201 21673587-21679900 protein_coding
  ENSDART00000101776 chek1-202 21673587-21679900 protein_coding
  ENSDART00000137423 chek1-001 21673131-21680230 protein_coding
  ENSDART00000138666 chek1-003 21673256-21678201 protein_coding
  ENSDART00000145977 chek1-002 21673200-21678339 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000065538ENSDART00000137423ENSDART00000145977
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000065538 N/A N/A N/A N/A 0.107±0.00
ENSDART00000137423 0.379±0.04 0.202±0.11 N/A 0.139±0.00 N/A
ENSDART00000145977 N/A N/A 2.680±0.00 0.085±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005622 IGI intracellular
GO:0006468 IEA protein phosphorylation
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0008630 IGI intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000149554 CHEK1 checkpoint kinase 1 protein_coding Homo_sapiens
ENSMUSG00000032113 Chek1 checkpoint kinase 1 protein_coding Mus_musculus

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