C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: catenin (cadherin-associated protein), beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000014571 ctnnb1 7955 - 16:7435502-7458987 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000038495 ctnnb1-001 7435502-7458987 protein_coding
  ENSDART00000148379 ctnnb1-003 7444084-7445836 protein_coding
  ENSDART00000148751 ctnnb1-002 7436177-7441963 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000038495
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000038495 46.387±26.69 195.313±110.30 45.030±26.55 6.577±0.00 19.224±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000578 IMP embryonic axis specification
GO:0001569 IBA patterning of blood vessels
GO:0001658 IBA branching involved in ureteric bud morphogenesis
GO:0001702 IBA gastrulation with mouth forming second
GO:0001711 IBA endodermal cell fate commitment
GO:0001889 IGI liver development
GO:0003136 IBA negative regulation of heart induction by canonical Wnt receptor signaling pathway
GO:0003337 IBA mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003713 IBA transcription coactivator activity
GO:0005198 IBA structural molecule activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0005829 IBA cytosol
GO:0005902 IDA microvillus
GO:0005912 IDA adherens junction
GO:0005913 IDA cell-cell adherens junction
GO:0005915 IDA zonula adherens
GO:0005916 IBA fascia adherens
GO:0005938 IDA cell cortex
GO:0007016 IBA cytoskeletal anchoring at plasma membrane
GO:0007155 IC cell adhesion
GO:0007160 IBA cell-matrix adhesion
GO:0007398 IGI ectoderm development
GO:0007403 IBA glial cell fate determination
GO:0009898 IBA cytoplasmic side of plasma membrane
GO:0009950 IBA dorsal/ventral axis specification
GO:0009953 IMP dorsal/ventral pattern formation
GO:0009954 IBA proximal/distal pattern formation
GO:0014010 IBA Schwann cell proliferation
GO:0014704 IDA intercalated disc
GO:0016020 IDA membrane
GO:0016323 IBA basolateral plasma membrane
GO:0016337 IBA cell-cell adhesion
GO:0016342 IDA catenin complex
GO:0019901 IBA protein kinase binding
GO:0022009 IBA central nervous system vasculogenesis
GO:0030018 IBA Z disc
GO:0030027 IBA lamellipodium
GO:0030326 IBA embryonic limb morphogenesis
GO:0030539 IBA male genitalia development
GO:0030902 IBA hindbrain development
GO:0031016 IBA pancreas development
GO:0031528 IBA microvillus membrane
GO:0032331 IBA negative regulation of chondrocyte differentiation
GO:0042475 IBA odontogenesis of dentin-containing tooth
GO:0043066 IBA negative regulation of apoptotic process
GO:0043123 IBA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043198 IBA dendritic shaft
GO:0043410 IBA positive regulation of MAPK cascade
GO:0043587 IBA tongue morphogenesis
GO:0043627 IBA response to estrogen
GO:0045202 IBA synapse
GO:0045294 IBA alpha-catenin binding
GO:0045296 IDA cadherin binding
GO:0045669 IBA positive regulation of osteoblast differentiation
GO:0045671 IBA negative regulation of osteoclast differentiation
GO:0045743 IBA positive regulation of fibroblast growth factor receptor signaling pathway
GO:0048262 IDA determination of dorsal/ventral asymmetry
GO:0048489 IBA synaptic vesicle transport
GO:0048599 IBA oocyte development
GO:0048617 IBA embryonic foregut morphogenesis
GO:0050808 IBA synapse organization
GO:0051145 IBA smooth muscle cell differentiation
GO:0060026 IGI convergent extension
GO:0060070 IGI canonical Wnt receptor signaling pathway
GO:0060441 IBA epithelial tube branching involved in lung morphogenesis
GO:0060769 IBA positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0072033 IBA renal vesicle formation
GO:0072053 IBA renal inner medulla development
GO:0072054 IBA renal outer medulla development
GO:0072079 IBA nephron tubule formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000168036 CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa protein_coding Homo_sapiens
ENSMUSG00000006932 Ctnnb1 catenin (cadherin associated protein), beta 1 protein_coding Mus_musculus

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