C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate decarboxylase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000015537 gad2 7955 - 24:6216526-6242312 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000021609 gad2-001 6216526-6242312 protein_coding
  ENSDART00000114229 gad2-201 6216530-6242226 protein_coding
  ENSDART00000147427 gad2-002 6241484-6242257 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000021609ENSDART00000114229
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000021609 102.401±78.78 0.152±0.08 0.197±0.10 0.130±0.00 6.056±0.00
ENSDART00000114229 N/A N/A N/A 0.132±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004351 IEA glutamate decarboxylase activity
GO:0005575 ND cellular_component
GO:0006520 IEA cellular amino acid metabolic process
GO:0009449 IEP gamma-aminobutyric acid biosynthetic process
GO:0016829 IEA lyase activity
GO:0016831 IEA carboxy-lyase activity
GO:0019752 IEA carboxylic acid metabolic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0042136 IEP neurotransmitter biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000136750 GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) protein_coding Homo_sapiens
ENSMUSG00000026787 Gad2 glutamic acid decarboxylase 2 protein_coding Mus_musculus

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