C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamic acid decarboxylase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026787 Gad2 10090 + 2:22622205-22693874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028123 Gad2-001 22622205-22693874 protein_coding
  ENSMUST00000156728 Gad2-002 22623304-22630001 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000028123ENSMUST00000156728
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000028123 0.014±0.01 0.018±0.00 0.005±0.00 14.505±2.28 0.011±0.00 0.081±0.04 0.016±0.00 0.013±0.01 0.015±0.01 0.016±0.01 0.069±0.04 0.009±0.00 0.163±0.08
ENSMUST00000156728 N/A N/A N/A N/A N/A 0.271±0.15 N/A N/A 0.008±0.00 N/A 0.033±0.00 N/A 0.488±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XV CIL_0001XV_0002 CGP 2:22227503-22693874
CIL_0000R5 CIL_0000R5_0002 CGP 2:22622205-22875653

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004351 IEA glutamate decarboxylase activity
GO:0005515 IEA protein binding
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006540 IEA glutamate decarboxylation to succinate
GO:0016595 IEA glutamate binding
GO:0030054 IEA cell junction
GO:0030424 IDA axon
GO:0030672 IEA synaptic vesicle membrane
GO:0031225 IEA anchored component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0042136 IEA neurotransmitter biosynthetic process
GO:0042493 IEA response to drug
GO:0045202 IDA synapse
GO:0046982 IEA protein heterodimerization activity
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015537 gad2 glutamate decarboxylase 2 protein_coding Danio_rerio
ENSG00000136750 GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) protein_coding Homo_sapiens

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