C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lin-28 homolog A (C. elegans)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000016999 lin28a 7955 + 19:14873056-14901221 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000098970 lin28a-001 14873056-14901221 protein_coding
  ENSDART00000135923 lin28a-003 14875387-14884660 protein_coding
  ENSDART00000140276 lin28a-002 14873153-14876422 protein_coding
  ENSDART00000142509 lin28a-004 14876244-14900282 protein_coding
  ENSDART00000146548 lin28a-005 14875415-14884987 retained_intron
  ENSDART00000151732 lin28a-006 14875097-14900479 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000098970ENSDART00000135923ENSDART00000142509ENSDART00000151732
Transcript ID Brain Heart Kidney Liver
ENSDART00000098970 0.106±0.05 0.012±0.00 1.829±0.00 0.142±0.00
ENSDART00000135923 0.665±0.00 N/A N/A N/A
ENSDART00000142509 0.285±0.00 N/A N/A N/A
ENSDART00000151732 0.286±0.00 0.139±0.00 N/A 0.145±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003723 ISS RNA binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0008270 IEA zinc ion binding
GO:0010494 ISS cytoplasmic stress granule
GO:0010587 ISS miRNA catabolic process
GO:0010629 IMP negative regulation of gene expression
GO:0019827 ISS stem cell maintenance
GO:0031047 IEA gene silencing by RNA
GO:0031054 ISS pre-miRNA processing
GO:0031099 IMP regeneration
GO:0031123 ISS RNA 3'-end processing
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000131914 LIN28A lin-28 homolog A (C. elegans) protein_coding Homo_sapiens
ENSMUSG00000050966 Lin28a lin-28 homolog A (C. elegans) protein_coding Mus_musculus

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