C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinase insert domain receptor (a type III receptor tyrosine kinase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000017321 kdr 7955 + 20:22293148-22349704 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000049204 kdr-001 22293148-22349704 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverMuscleENSDART00000049204
Transcript ID Brain Heart Liver Muscle
ENSDART00000049204 2.258±1.83 6.224±0.00 1.168±0.00 3.792±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001525 IGI angiogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005021 IEA vascular endothelial growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005769 IEA early endosome
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral to plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019838 IEA growth factor binding
GO:0030054 IEA cell junction
GO:0030154 IEA cell differentiation
GO:0031410 IEA cytoplasmic vesicle
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000128052 KDR kinase insert domain receptor (a type III receptor tyrosine kinase) protein_coding Homo_sapiens
ENSMUSG00000062960 Kdr kinase insert domain protein receptor protein_coding Mus_musculus

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