C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor protein p73
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000017953 tp73 7955 + 8:51108387-51195663 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000079644 tp73-002 51118336-51195268 protein_coding
  ENSDART00000124737 tp73-201 51108387-51195345 protein_coding
  ENSDART00000130673 tp73-001 51108387-51195663 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000079644ENSDART00000124737ENSDART00000130673
Transcript ID Brain Heart Kidney Liver
ENSDART00000079644 N/A 0.063±0.03 0.096±0.00 0.016±0.00
ENSDART00000124737 0.070±0.04 N/A N/A N/A
ENSDART00000130673 0.139±0.07 N/A 0.461±0.29 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006BL CIL_0006BL_0001 CGP 8:51076269-51195663

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IBA chromatin
GO:0002039 IBA p53 binding
GO:0003677 IEA DNA binding
GO:0003682 IBA chromatin binding
GO:0003684 IBA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005667 IBA transcription factor complex
GO:0005829 IBA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006915 IEA apoptotic process
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0010165 IBA response to X-ray
GO:0010332 IBA response to gamma radiation
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0034644 IBA cellular response to UV
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043508 IBA negative regulation of JUN kinase activity
GO:0043524 IBA negative regulation of neuron apoptotic process
GO:0043565 IBA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0051262 IEA protein tetramerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000078900 TP73 tumor protein p73 protein_coding Homo_sapiens
ENSMUSG00000029026 Trp73 transformation related protein 73 protein_coding Mus_musculus

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