C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor protein p73
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078900 TP73 9606 + 1:3652520-3736201 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346387 TP73-201 3652565-3736200 protein_coding
  ENST00000354437 TP73-002 3652565-3733292 protein_coding
  ENST00000357733 TP73-202 3652565-3736200 protein_coding
  ENST00000378280 TP73-005 3690672-3733292 protein_coding
  ENST00000378285 TP73-004 3690672-3733292 protein_coding
  ENST00000378288 TP73-003 3690672-3736201 protein_coding
  ENST00000378290 TP73-007 3698058-3733091 protein_coding
  ENST00000378295 TP73-001 3652520-3736201 protein_coding
  ENST00000603362 TP73-012 3682366-3733079 protein_coding
  ENST00000603364 TP73-009 3690707-3729751 retained_intron
  ENST00000604074 TP73-006 3652520-3736201 protein_coding
  ENST00000604194 TP73-008 3698046-3708534 retained_intron
  ENST00000604479 TP73-013 3682366-3733079 protein_coding
  ENST00000604566 TP73-011 3727478-3733367 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryENST00000378285
Transcript ID Ovary
ENST00000378285 0.372±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BY CIL_0002BY_0002 CGP 1:3625002-3652761
CIL_0006BL CIL_0006BL_0002 CGP 1:3630767-3736201

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000187 IEA activation of MAPK activity
GO:0000785 IBA chromatin
GO:0001822 IEA kidney development
GO:0001836 IEA release of cytochrome c from mitochondria
GO:0002039 IBA p53 binding
GO:0003677 IEA DNA binding
GO:0003682 IBA chromatin binding
GO:0003684 IBA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0005829 IBA cytosol
GO:0006298 TAS mismatch repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006954 IEA inflammatory response
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007050 IEA cell cycle arrest
GO:0008134 IPI transcription factor binding
GO:0008630 TAS intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009791 IEA post-embryonic development
GO:0010165 IBA response to X-ray
GO:0010243 IEA response to organonitrogen compound
GO:0010332 IBA response to gamma radiation
GO:0019901 IPI protein kinase binding
GO:0021766 IEA hippocampus development
GO:0030900 IEA forebrain development
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0033326 IEA cerebrospinal fluid secretion
GO:0034644 IBA cellular response to UV
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 IPI identical protein binding
GO:0043065 IEA positive regulation of apoptotic process
GO:0043508 IBA negative regulation of JUN kinase activity
GO:0043523 IEA regulation of neuron apoptotic process
GO:0043524 IBA negative regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA:IEA transcription regulatory region DNA binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045793 IEA positive regulation of cell size
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048546 IEA digestive tract morphogenesis
GO:0048666 IEA neuron development
GO:0048714 IEA positive regulation of oligodendrocyte differentiation
GO:0051262 IEA protein tetramerization
GO:1902167 IEA positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017953 tp73 tumor protein p73 protein_coding Danio_rerio
ENSMUSG00000029026 Trp73 transformation related protein 73 protein_coding Mus_musculus

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