C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Parkinson disease (autosomal recessive, juvenile) 2, parkin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000021555 park2 7955 - 13:3044126-3168325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000029649 park2-001 3044126-3059869 protein_coding
  ENSDART00000146240 park2-002 3126610-3168325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000029649ENSDART00000146240
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000029649 4.803±0.84 3.600±0.00 N/A 2.230±0.00 7.079±0.00
ENSDART00000146240 12.622±3.20 15.775±8.07 26.248±0.00 6.183±0.00 12.336±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein ligase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IEA cytosol
GO:0006120 IMP mitochondrial electron transport, NADH to ubiquinone
GO:0006979 IDA response to oxidative stress
GO:0008270 IEA zinc ion binding
GO:0009266 IMP response to temperature stimulus
GO:0016881 IEA acid-amino acid ligase activity
GO:0042981 IDA regulation of apoptotic process
GO:0046872 IEA metal ion binding
GO:0051865 IDA protein autoubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000185345 PARK2 parkin RBR E3 ubiquitin protein ligase protein_coding Homo_sapiens
ENSMUSG00000023826 Park2 Parkinson disease (autosomal recessive, juvenile) 2, parkin protein_coding Mus_musculus

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