C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: toll-like receptor 4b, duplicate b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000022048 tlr4bb 7955 + 13:18572634-18577835 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000034852 tlr4bb-001 18572634-18577835 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000034852
Transcript ID Brain Heart Kidney Muscle
ENSDART00000034852 0.031±0.01 0.253±0.09 0.155±0.08 0.039±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 IEA toll-like receptor signaling pathway
GO:0002755 IEA MyD88-dependent toll-like receptor signaling pathway
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IEA protein binding
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0007165 IEA signal transduction
GO:0016021 IEA integral to membrane
GO:0034130 IEA toll-like receptor 1 signaling pathway
GO:0042116 IEA macrophage activation
GO:0042495 IEA detection of triacyl bacterial lipopeptide
GO:0045087 IEA innate immune response
GO:0050707 IEA regulation of cytokine secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000136869 TLR4 toll-like receptor 4 protein_coding Homo_sapiens
ENSMUSG00000039005 Tlr4 toll-like receptor 4 protein_coding Mus_musculus

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