C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: topoisomerase (DNA) II alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000024488 top2a 7955 + 12:11702259-11719558 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000106152 top2a-001 11702259-11719558 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000106152
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000106152 0.793±0.55 0.968±0.55 20.283±0.00 0.493±0.00 0.678±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003918 IEA DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005524 IEA ATP binding
GO:0006265 IEA DNA topological change

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000131747 TOP2A topoisomerase (DNA) II alpha 170kDa protein_coding Homo_sapiens
ENSMUSG00000020914 Top2a topoisomerase (DNA) II alpha protein_coding Mus_musculus

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