C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000025032 nr3c1 7955 - 14:24652384-24705620 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000054264 nr3c1-201 24652384-24705620 protein_coding
  ENSDART00000124144 nr3c1-001 24652783-24703577 protein_coding
  ENSDART00000124401 nr3c1-002 24667182-24703580 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartLiverMuscleENSDART00000054264ENSDART00000124144
Transcript ID Heart Liver Muscle
ENSDART00000054264 4.143±0.00 0.675±0.00 N/A
ENSDART00000124144 N/A N/A 1.582±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004883 IEA glucocorticoid receptor activity
GO:0005496 IEA steroid binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0008270 IEA zinc ion binding
GO:0009790 IMP embryo development
GO:0042921 IEA glucocorticoid receptor signaling pathway
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043402 IEA glucocorticoid mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-dependent
GO:0046872 IEA metal ion binding
GO:0051384 IMP response to glucocorticoid
GO:0051414 IDA response to cortisol
GO:0070509 IMP calcium ion import
GO:0071548 IDA response to dexamethasone

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000113580 NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) protein_coding Homo_sapiens
ENSMUSG00000024431 Nr3c1 nuclear receptor subfamily 3, group C, member 1 protein_coding Mus_musculus

Loading