C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 3, group C, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024431 Nr3c1 10090 - 18:39410545-39491301 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025300 Nr3c1-002 39411987-39489846 protein_coding
  ENSMUST00000097592 Nr3c1-004 39414482-39487232 protein_coding
  ENSMUST00000115567 Nr3c1-001 39410545-39490674 protein_coding
  ENSMUST00000115571 Nr3c1-201 39410547-39487245 protein_coding
  ENSMUST00000124115 Nr3c1-005 39486844-39491301 protein_coding
  ENSMUST00000131885 Nr3c1-007 39487086-39489283 protein_coding
  ENSMUST00000150483 Nr3c1-006 39487160-39491299 protein_coding
  ENSMUST00000152853 Nr3c1-003 39424436-39489888 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025300ENSMUST00000115567ENSMUST00000115571ENSMUST00000152853
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025300 N/A N/A N/A N/A 2.100±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000115567 5.067±0.36 2.739±0.57 4.657±0.34 0.280±0.06 4.027±0.98 5.821±0.00 1.964±1.04 5.025±1.80 3.422±2.75 6.897±1.62 2.973±1.25 3.809±1.96 1.022±0.50 0.279±0.09
ENSMUST00000115571 13.198±7.35 N/A 10.629±0.70 2.732±2.73 9.695±2.51 3.637±1.37 3.909±1.18 5.539±1.73 3.586±1.58 12.161±5.80 7.265±1.74 4.337±2.67 3.397±2.05 0.412±0.10
ENSMUST00000152853 N/A 1.813±0.43 N/A N/A 3.523±0.23 3.225±0.14 N/A N/A N/A 8.648±0.00 N/A 1.471±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004883 IDA glucocorticoid receptor activity
GO:0005496 IEA steroid binding
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006111 IMP regulation of gluconeogenesis
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0008211 IMP glucocorticoid metabolic process
GO:0008270 IEA zinc ion binding
GO:0016020 IDA membrane
GO:0030325 IMP adrenal gland development
GO:0031946 IMP regulation of glucocorticoid biosynthetic process
GO:0042711 IGI maternal behavior
GO:0042921 IMP glucocorticoid receptor signaling pathway
GO:0043402 IEA:IDA glucocorticoid mediated signaling pathway
GO:0043525 IGI positive regulation of neuron apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IDA protein dimerization activity
GO:0060603 IMP mammary gland duct morphogenesis
GO:1900170 IDA negative regulation of glucocorticoid mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025032 nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) protein_coding Danio_rerio
ENSG00000113580 NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) protein_coding Homo_sapiens

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