C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000026294 erbb2 7955 - 12:10108666-10192429 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000003932 erbb2-001 10114523-10192429 protein_coding
  ENSDART00000114258 erbb2-201 10108666-10192257 protein_coding
  ENSDART00000135041 erbb2-002 10114518-10118075 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000003932ENSDART00000114258
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000003932 N/A N/A N/A 2.403±0.00 N/A
ENSDART00000114258 0.741±0.00 9.918±5.71 13.490±0.00 2.364±0.00 1.114±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001755 IMP neural crest cell migration
GO:0001837 IMP epithelial to mesenchymal transition
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007413 IMP axonal fasciculation
GO:0014037 IMP Schwann cell differentiation
GO:0014044 IMP Schwann cell development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031101 IMP fin regeneration
GO:0032285 IMP non-myelinated axon ensheathment
GO:0042552 IMP myelination
GO:0048914 IMP myelination of anterior lateral line nerve axons
GO:0048919 IMP posterior lateral line neuromast development
GO:0048932 IMP myelination of posterior lateral line nerve axons
GO:0060347 IMP heart trabecula formation
GO:0060973 IMP cell migration involved in heart development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000141736 ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 protein_coding Homo_sapiens
ENSMUSG00000062312 Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) protein_coding Mus_musculus

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