C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitochondrial topoisomerase I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000027824 top1mt 7955 + 24:43770846-43780260 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000025550 top1mt-201 43770846-43780260 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000025550
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000025550 0.982±0.35 1.382±0.25 7.432±6.94 1.441±0.00 1.159±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003917 IEA DNA topoisomerase type I activity
GO:0003918 IEA DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005694 IEA chromosome
GO:0006265 IEA DNA topological change

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000198900 TOP1 topoisomerase (DNA) I protein_coding Homo_sapiens
ENSMUSG00000070544 Top1 topoisomerase (DNA) I protein_coding Mus_musculus

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