C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNF receptor-associated factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000028058 traf6 7955 - 7:50179826-50195706 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000038273 traf6-001 50179826-50195706 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000038273
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000038273 1.274±0.63 3.072±0.39 3.417±0.00 1.182±0.00 2.539±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0001503 IEA ossification
GO:0004842 IEA ubiquitin-protein ligase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007165 IEA signal transduction
GO:0007250 IEA activation of NF-kappaB-inducing kinase activity
GO:0008270 IEA zinc ion binding
GO:0009615 IDA response to virus
GO:0009617 IDA response to bacterium
GO:0009887 IEA organ morphogenesis
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031666 IEA positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0042981 IEA regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0043565 IEA sequence-specific DNA binding
GO:0045087 IMP innate immune response
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0045893 IDA positive regulation of transcription, DNA-dependent
GO:0046849 IEA bone remodeling
GO:0046872 IEA metal ion binding
GO:0048468 IEA cell development
GO:0050852 IEA T cell receptor signaling pathway
GO:0051865 IEA protein autoubiquitination
GO:0070498 IEA interleukin-1-mediated signaling pathway
GO:0070534 ISS protein K63-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000175104 TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase protein_coding Homo_sapiens
ENSMUSG00000027164 Traf6 TNF receptor-associated factor 6 protein_coding Mus_musculus

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