C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000032116 cnot7 7955 + 14:31283387-31294483 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000092953 cnot7-001 31283387-31294483 protein_coding
  ENSDART00000136009 cnot7-003 31283406-31294483 nonsense_mediated_decay
  ENSDART00000142583 cnot7-002 31284691-31292816 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000092953ENSDART00000136009
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000092953 1.839±0.87 2.479±0.84 3.757±0.57 0.226±0.00 0.850±0.00
ENSDART00000136009 0.168±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 ISS 3'-5'-exoribonuclease activity
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0004518 IEA nuclease activity
GO:0004527 IEA exonuclease activity
GO:0004535 IEA poly(A)-specific ribonuclease activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006417 IEA regulation of translation
GO:0008284 ISS positive regulation of cell proliferation
GO:0008285 ISS negative regulation of cell proliferation
GO:0016787 IEA hydrolase activity
GO:0030014 ISS CCR4-NOT complex
GO:0031047 ISS gene silencing by RNA
GO:0043928 ISS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0046872 IEA metal ion binding
GO:0060213 ISS positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090305 ISS nucleic acid phosphodiester bond hydrolysis
GO:1900153 ISS positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000198791 CNOT7 CCR4-NOT transcription complex, subunit 7 protein_coding Homo_sapiens
ENSMUSG00000031601 Cnot7 CCR4-NOT transcription complex, subunit 7 protein_coding Mus_musculus

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