C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031601 Cnot7 10090 - 8:40492540-40515847 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034012 Cnot7-001 40492540-40511754 protein_coding
  ENSMUST00000128237 Cnot7-007 40510023-40515835 processed_transcript
  ENSMUST00000132032 Cnot7-006 40492542-40515847 protein_coding
  ENSMUST00000132200 Cnot7-010 40500733-40507585 processed_transcript
  ENSMUST00000132740 Cnot7-011 40495597-40507668 retained_intron
  ENSMUST00000135269 Cnot7-003 40492547-40511718 protein_coding
  ENSMUST00000139558 Cnot7-008 40510103-40511304 processed_transcript
  ENSMUST00000142455 Cnot7-009 40494014-40501072 processed_transcript
  ENSMUST00000144970 Cnot7-004 40492543-40511718 retained_intron
  ENSMUST00000146280 Cnot7-002 40507318-40511722 processed_transcript
  ENSMUST00000149992 Cnot7-005 40493036-40511304 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034012ENSMUST00000132032ENSMUST00000132200ENSMUST00000135269ENSMUST00000139558ENSMUST00000146280ENSMUST00000149992
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034012 5.908±3.05 22.164±1.27 13.021±1.24 20.362±9.80 4.339±1.81 6.330±2.74 5.770±0.74 5.812±1.76 7.786±3.53 9.506±1.20 13.571±0.89 10.905±3.96 10.963±4.30 9.862±4.16
ENSMUST00000132032 N/A N/A N/A N/A 1.798±0.00 N/A N/A N/A 1.219±0.19 N/A N/A 16.544±0.61 7.355±0.00 N/A
ENSMUST00000132200 N/A N/A N/A 231.959±0.00 N/A N/A N/A N/A N/A N/A N/A 261.482±0.00 201.681±57.71 201.380±0.00
ENSMUST00000135269 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.220±0.00 3.617±0.00 N/A
ENSMUST00000139558 N/A N/A N/A N/A N/A 3.548±0.00 N/A 4.701±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000146280 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 27.786±0.00 N/A
ENSMUST00000149992 3.054±1.30 N/A 3.195±0.35 17.417±0.48 2.791±0.92 1.556±0.11 1.374±0.00 1.440±0.09 2.367±1.02 4.724±0.09 N/A 5.617±2.08 5.591±0.39 3.471±2.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000454 CIL_000454_0002 CGP 8:40307458-40510268
CIL_0001VB CIL_0001VB_0002 CGP 8:40423815-40515847
CIL_0001T6 CIL_0001T6_0002 CGP 8:40492540-40551134

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 ISS 3'-5'-exoribonuclease activity
GO:0000289 IMP nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 IGI deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0004532 ISS exoribonuclease activity
GO:0004535 IMP poly(A)-specific ribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008284 ISS positive regulation of cell proliferation
GO:0008285 ISS negative regulation of cell proliferation
GO:0016020 IEA membrane
GO:0030014 IPI CCR4-NOT complex
GO:0031047 IMP gene silencing by RNA
GO:0033962 IGI cytoplasmic mRNA processing body assembly
GO:0043928 ISS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0060213 ISS positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 ISS positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032116 cnot7 CCR4-NOT transcription complex, subunit 7 protein_coding Danio_rerio
ENSG00000198791 CNOT7 CCR4-NOT transcription complex, subunit 7 protein_coding Homo_sapiens

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