C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198791 CNOT7 9606 - 8:17224964-17246878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361272 CNOT7-001 17224964-17246878 protein_coding
  ENST00000518021 CNOT7-005 17242994-17246857 nonsense_mediated_decay
  ENST00000518541 CNOT7-012 17230568-17234860 protein_coding
  ENST00000518885 CNOT7-009 17244327-17246572 processed_transcript
  ENST00000519918 CNOT7-011 17234593-17245091 protein_coding
  ENST00000519954 CNOT7-006 17232329-17246857 nonsense_mediated_decay
  ENST00000519998 CNOT7-003 17241294-17245052 retained_intron
  ENST00000520178 CNOT7-008 17243181-17246448 protein_coding
  ENST00000522062 CNOT7-010 17234801-17237595 retained_intron
  ENST00000523649 CNOT7-004 17244740-17246865 retained_intron
  ENST00000523917 CNOT7-002 17231570-17246878 protein_coding
  ENST00000524358 CNOT7-007 17237242-17246609 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361272ENST00000523917
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361272 3.307±0.00 4.774±0.00 7.032±0.00 9.510±1.65 4.415±0.69 9.535±4.42 2.107±0.00 4.318±1.81 5.473±4.03 8.574±5.64 4.310±1.58 6.963±4.70 4.772±0.38 6.151±1.35
ENST00000523917 6.970±0.00 6.857±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VB CIL_0001VB_0001 CGP 8:17156029-17246878
CIL_0001T6 CIL_0001T6_0001 CGP 8:17224964-17302427

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 IEA deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0003676 IEA nucleic acid binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003723 IEA RNA binding
GO:0004532 IDA exoribonuclease activity
GO:0004535 IDA poly(A)-specific ribonuclease activity
GO:0004871 TAS signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0007165 TAS signal transduction
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030014 IDA CCR4-NOT complex
GO:0031047 ISS gene silencing by RNA
GO:0033962 IEA cytoplasmic mRNA processing body assembly
GO:0035195 TAS gene silencing by miRNA
GO:0043928 IDA exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0060213 IMP positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 IMP positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032116 cnot7 CCR4-NOT transcription complex, subunit 7 protein_coding Danio_rerio
ENSMUSG00000031601 Cnot7 CCR4-NOT transcription complex, subunit 7 protein_coding Mus_musculus

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